Vertex Pharmaceuticals Incorporated(VRTX)
NASDAQ
$505.64
3.33 (0.66%)

Vertex Pharmaceuticals Incorporated(VRTX)Stock Price & Analysis
NASDAQ

VRTX Stock Price Today (October 2026) — Vertex Pharmaceuticals Incorporated Analysis & Key Metrics 2026-10-07

Vertex Pharmaceuticals Incorporated (VRTX) is trading at $505.64, up 0.66% today (as of October 2026). The stock continues to show mixed signals with a short-term dip within a broader uptrend, attracting attention from investors looking for Healthcare growth opportunities.

  • According to consensus analyst estimates, the 1-year price target is $571.39 (13.0% upside).
  • Volatility is low (14.66% annualized), implying relatively contained price movements for short-term traders.
  • The fundamental picture, based on the latest financial filings, is nuanced: solid revenue growth (12.50% YoY) alongside competitive pressures in the Biotechnology space.

VRTX Stock Analysis: Key Metrics & Valuation (October 2026)

Concise, actionable data for investors

Trend posture
Short-term pullback in long-term uptrend
Analyst 1Y target$571.39+13.0%
Volatility (30d ann.)14.66%Low
RSI (14-day)
37.51 (Neutral)
Debt$1.98B (0.10x D/E)

Vertex Pharmaceuticals Incorporated - Historical Price & Volume

$505.64
+37.67 (+8.05%)
  • Price
  • Volume
  • Latest price
Range: 2Y

Market Cap

$128.16B

Enterprise Value: $122.29B

P/E Ratio

30.10

Forward P/E: 24.75

Revenue Growth

+12.50%

Year over Year

Analyst Target

$571.39

+13.0% upside potential

Key Investor Questions About VRTX

What investors need to know before buying

Is it a good time to buy VRTX stock?

Based on current market data, VRTX presents a neutral technical setup with looking solid fundamentals.

  • Technicals say: Neutral (RSI 37.51)
  • Fundamentals say: Looking solid (debt and growth supportive)
Can VRTX sustain revenue growth in the Biotechnology market?

VRTX's growth trajectory depends on its ability to expand within the Biotechnology sector while managing margin pressures.

  • Future growth will depend on performance in core Biotechnology operations.
  • The ability to manage competitive pressures will be crucial for sustained growth.
What are the biggest risks facing VRTX stock?

The primary risks for VRTX investors include debt exposure and competitive dynamics in the Biotechnology industry.

  • $1.98B in debt could be a headwind in a high-rate environment.
  • Fierce competition from established players in Biotechnology.

52-Week Trading Range

52-Week Low$400.74
52-Week High$560.25
Current Price$505.64

Over the past year, VRTX stock traded between $400.74 and $560.25 and currently trades in the middle of that range. Big swings are less likely unless a major catalyst emerges.

Volatility & Risk Profile

30-Day Volatility14.66%
Beta0.64
RSI (14-day)37.51

With 14.66% annualized volatility and β=0.64, the stock exhibits low sensitivity to market moves—making VRTX suitable for investors comfortable with active risk management.

Institutional & Insider Ownership

Insider Ownership0.21%
Institutional Ownership97.95%
Shares Short4.72M

High institutional ownership with low short interest suggests steadier hands and low immediate risk.

Analyst Sentiment & Price Targets

Mean Target
$571.39
Upside Potential
+13.0%
Recommendation
buy
Analysts maintain moderate optimism with a $571.39 target, indicating13.0% upside potential.

Latest News & Headlines

Recent headlines and coverage

Simply Wall St.Sep 25, 2026

Maze Therapeutics (MAZE) Shares Moved, So What Is Driving Attention Now?

Fresh Coverage Puts Maze Therapeutics in Focus Maze Therapeutics (MAZE) moved higher in pre-market trading on 23 September after CIBC began covering the clinical-stage kidney and metabolic disease specialist, with the share reaction unfolding alongside new kidney data from Vertex Pharmaceuticals. Recent trading has been choppy for Maze Therapeutics, with a 1-day share price return that declined 6.69% following a 7-day share price return up 11.82%. The year-to-date share price return is down...

ZacksSep 24, 2026

Vertex Pharmaceuticals (VRTX) Increases Despite Market Slip: Here's What You Need to Know

Vertex Pharmaceuticals (VRTX) closed at $522.38 in the latest trading session, marking a +1.17% move from the prior day.

ZacksSep 24, 2026

Will Vertex's Kidney Disease Pipeline Be a New Growth Engine?

VRTX is expanding beyond its CF stronghold with a promising kidney disease pipeline led by povetacicept and inaxaplin.

BioPharma DiveSep 24, 2026

Lilly’s latest China drug deal; Immunovant’s setback in lupus

Lilly wagered up to $3.35 billion in its fourth China-focused alliance since January 2025. Elsewhere, analysts are now more confident about one of Vertex’s top prospects and an RNA drug succeeded against a rare form of ALS.

Motley FoolSep 24, 2026

CRISPR Therapeutics vs. Vertex Pharmaceuticals: Which Healthcare Stock Is a Better Buy in 2026?

One is burning cash while chasing gene-editing breakthroughs. The other generates billions from a single therapy. Their divergent paths reveal starkly different risk-reward profiles.

Simply Wall St.Sep 24, 2026

Vertex (VRTX) Stock Could Be 24% Undervalued As Kidney Trial Progress Continues

Vertex Pharmaceuticals has ridden a powerful five year share price run while pushing deeper into kidney disease, endocrinology and pain treatments, which puts fresh attention on what investors are really paying for its cash flows today. With the stock near recent highs after a series of clinical and commercial updates, the open question is whether the current market price lines up with the cash the business is expected to generate over time. Over the past 5 years, Vertex Pharmaceuticals has...

ZacksSep 23, 2026

Vertex Posts Positive Phase II Data on Kidney Disease Drug

VRTX announces positive AMPLIFIED data for inaxaplin, while completing AMPLITUDE enrollment and targeting interim results in early 2027.

Investor's Business DailySep 22, 2026

The Surprise That Sent Vertex — And Its Chief Rival — Soaring

Vertex stock popped Tuesday — while shares of rival Maze Therapeutics skyrocketed — on a surprise expansion for their kidney disease drugs.

StocktwitsSep 22, 2026

Twin Moves: VRTX Rises On Kidney Disease Trial Results, MAZE Rallies Harder

Vertex on Tuesday announced results from the mid-stage trial of its experimental pill, inaxaplin, in two groups of patients with APOL1-mediated kidney disease.

Barrons.comSep 22, 2026

Vertex’s Kidney Drug Success Sparks a 22% Surge for This Rival Biotech

Maze Therapeutics stock jumped after Vertex Pharmaceuticals reported positive results for inaxaplin, boosting confidence in a rival treatment from Maze.

Earnings snapshot

Next report Nov 2, 2026 (after the close, usually)

EPS beat rate
58% (7/12)
Avg move after earnings
±4.8%
Options-implied move
—
Options vs history
—
VRTX earnings history, charts and expected move

Frequently Asked Questions

Common investor questions about Vertex Pharmaceuticals Incorporated

Vertex Pharmaceuticals Incorporated (VRTX) is currently trading at $505.64. The RSI (14-day) is at 37.5, indicating neutral territory. Wall Street analysts have a consensus "buy" recommendation. The mean analyst price target of $571.39 implies 13.0% upside from current levels. Volatility is low at 14.7% annualized, meaning price movements are relatively contained. Investors should consider their risk tolerance, investment horizon, and portfolio diversification before making a decision.

Based on current valuation metrics for Vertex Pharmaceuticals Incorporated (VRTX): The trailing P/E ratio is 30.10, which is above the market average, indicating investors are pricing in higher growth expectations. The forward P/E is 24.75, lower than the trailing P/E, suggesting analysts expect earnings improvement. The PEG ratio is 1.90, near 1.0, suggesting roughly fair value relative to growth. Price-to-Book is 6.50. Price-to-Sales is 10.46. Valuation should be compared to Biotechnology industry peers for context, as different sectors trade at different multiples.

Based on 28 analysts covering VRTX, the consensus price target is $571.39. This represents a 13.0% upside from the current price of $505.64. The range spans from a low target of $350.00 to a high target of $672.00, reflecting varying levels of optimism among analysts. The consensus recommendation is "buy". Note: Analyst price targets are forward-looking estimates and not guarantees of future performance.

Vertex Pharmaceuticals Incorporated (VRTX) does not currently pay a regular dividend. The company may be reinvesting profits into growth initiatives, or may not yet be profitable enough to distribute earnings to shareholders.

Key risks for Vertex Pharmaceuticals Incorporated (VRTX) investors include: 1. Broader market and macroeconomic risks (interest rates, inflation, geopolitical events). 2. Biotechnology sector-specific competitive pressures. Investors should diversify and consider their risk tolerance before investing.

Here is Vertex Pharmaceuticals Incorporated's (VRTX) current debt and financial health profile: Total debt stands at $1.98B. The debt-to-equity ratio is 0.10x, which is conservative and indicates a strong balance sheet with low leverage. The current ratio is 3.19, indicating strong short-term liquidity. The quick ratio is 2.54. The company holds $7.85B in cash and equivalents. Free cash flow is positive at $2.63B, providing a cushion for debt servicing and shareholder returns.